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Therefore, an accurate in-cell measurement of redox potential could one day help us determine how well cells can recover from oxidative stress and, as a result, give us a picture of the cell's overall health." Currently, the NIST researchers are exploring other NMR-detectable peptides involved in reduction and oxidation processes to conduct studies with mammalian cells

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The reduction of roGFP2(S 2 ) according to monothiol mechanism (iii) and previous experiments in yeast also raise the question whether the dithiol mechanism is crucial for the reduction of many protein substrates 34