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In a placebo-controlled, crossover trial, 12 patients with Alzheimer’s disease who were treated daily for 6 weeks with dronabinol (synthetic delta-9-THC) displayed improvements in disturbed behavior [104]
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Conjugated bile acids (CBAs) can activate the ERK1/2 and Akt signaling pathways via S1PR2, exerting an inhibitory effect on apoptosis (55–57)
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