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The FGF19 subfamily of FGFs, consisting of FGF19, FGF21, and FGF23, is characterized by reduced affinity for heparan sulfate (HS) ( via the systemic circulation, as well as canonical FGF paracrine signaling on their cell of origin or nearby cells (38)
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C/EBPβ directly activates the transcription of ATGs such as ULK1, BNIP3 , GABARAPL1, MAP1LC3B , and SQSTM1 , supporting phagophore formation and substrate targeting
this bundle supports studies involving melanocortin receptor pathways and related biological functions
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