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Age remains the most significant risk factor for developing PD, and men are more susceptible than women with a prevalence ratio of approximately 3:2 (Tolosa et al., 2021), thereby exacerbating personal, social, and economic burdens

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Observed side effects in research environments are generally mild and temporary, most commonly including: Temporary fatigue-related observations Mild fluid-retention variability Increased hunger- or appetite-related observations Mild headache-related observations Minor administration-site irritation such as redness or temporary administration-site sensitivity observations Proper reconstitution, sterile handling practices, proper administration techniques, and regular administration-site rotation are important for minimizing local irritation and maintaining peptide stability and consistency during research use