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Alternative readouts help but fragment the picture: voltammetry and immunostrips deliver speed at the cost of scope, while capillary electrochromatography trades coverage for protracted runs [71,72]
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There are three additional cysteine residues in mammalian Trxs beyond those in the active site (cysteines 62, 69, and 73), and Cys73 has been shown to be S-nitrosated by GSNO when Trx is in its oxidized form [90]
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