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RACK1 acts as a scaffold to facilitate activation of FAK, and IGF-1 stimulates dephosphorylation of FAK, which is associated with dissolution of focal adhesions ( Thus, IGF-1R levels alone will not necessarily determine cancer cell responses to IGF-1 and anti-IGF-1R therapies, as IGF-1R activity and downstream signaling are influenced by adhesion signals and activation of other signaling pathways, which are discussed further below
Food supplement
Size:100mg
chez les souris et de 100 mg/kg p.c
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