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doi: 10.4103/tcmj.tcmj_134_24, 71 MolinaM
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Studies in the model organism Caenorhabditis elegans have demonstrated that different FOXO isoforms—particularly DAF-16A—exert a significant influence on lifespan extension by activating or repressing specific genes such as gst-20 and srr-4, which either promote or inhibit longevity-associated mechanisms
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