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Bioavailability is the degree and rate at which a substance is absorbed into the bloodstream and used by the body
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This raises the possibility that astrocytic Nrf2 activation (in boosting astrocytic GSH synthesis and supply of GSH precursors to neurons), would cooperate with synaptic activity (in boosting neuronal GSH biosynthetic capacity) in enabling the maintenance of neuronal GSH levels in the face of oxidative insults
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