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Two Subtypes of Astrocytes in Neuroinflammation In response to neuroinflammatory stimuli, astrocytes can polarize into two distinct functional phenotypes: the neurotoxic or pro‐inflammatory phenotype (A1) and the neuroprotective or anti‐inflammatory phenotype (A2), as illustrated in Figure 2
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We used primary lens epithelial cells from wild type mice and TTase knockout mice as a model and focused on studying the regulation and physiological function of LMW-PTP2, in particular the role in regulating PDGF mitogenic action
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