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La enfermedad de Niemann-Pick tipo C es una enfermedad neurovisceral, por tanto, los síntomas posibles son los sistémicos derivados de la afectación visceral (hígado, bazo y, menos frecuentemente, pulmón) y los neurológicos
Anti-Aging Complex
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Similarly, IP3 receptor type 2 knockout (Itpr2 − / − ) mice, which exhibit near-complete loss of astrocytic Ca 2+ transients, show depressive-like behaviors, aberrant brain-wide functional connectivity, and reduced frontal-limbic resting-state connectivity, all resembling alterations observed in MDD patients [140]
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