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Volume:150 ml Key mechanisms of SFN action involve the activation of MAPKs (SFN activates three mitogen-activated protein kinases (MAPKs): extracellular signal-regulated protein kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 MAPK), activation of PKC (SFN stimulates protein kinase C (PKC), which directly phosphorylates Nrf2) and PI3K/AKT pathway, because SFN activates phosphatidylinositol 3-kinase (PI3K) and protein kinase B (AKT), leading to Nrf2 activation [79] https://sa1s3optim.patientpop.com/filters:format(webp)/assets/images/provider/photos/2714075.png Asian Beauty FSP1-mediated ferroptosis in cancer: from mechanisms to therapeutic applications | Apoptosis | Springer Nature Link
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